徐志超教授，博士生導師
E-mail: zcxu@nefu.edu.cn
伟德官网下app官方网站（新逸夫教學樓507）
工作經曆
2021-05至現在，伟德官网下app官方网站，伟德官网下app官方网站，教授
2016-08至2021-05，中國醫學科學院藥用植物研究所，助理研究員，副研究員
2019-09至2020-09，VIB - UGent Center for Plant Systems Biology，訪問學者
研究領域
林源活性物質代謝合成及調控；合成生物學；本草基因組學；分子輔助育種；分子鑒定
科研項目（主持）
1. “功效-物質-遺傳”關聯的五味子優良品質形成機制研究，國自然區域重點（聯合）
2.酪氨酸衍生的中藥活性成分異源高效生物制造，國家重點研發計劃（任務）
3.瀕危藥材關黃柏活性成分小檗堿的生物合成機制研究，國自然面上項目
4.西紅花苷生源途徑解析及合成生物學研究，國自然面上項目
5.中藥多組學方法創新及新品種選育研究，國家重點研發計劃（課題）
6.丹參酮生物合成關鍵酶短鍊脫氫酶編碼基因的克隆和功能鑒定，國自然青年基金
代表性論文（第一及通訊，含共同，IF2022）
1. Lineage-specific CYP80 Expansion and Benzylisoquinoline Alkaloid Diversity in Early-diverging Eudicots.Advanced Science, 2024, 2309990 (IF=15.1)
2. Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis.Nature Communications, 2023, 14: 6470 (IF=16.6)Highlight
3. Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genusSalvia.Nature Communications, 2023, 14: 4696 (IF=16.6)
4. Cepharanthine analogs mining and genomes ofStephaniaaccelerate anti-coronavirus drug discovery.Nature Communications, 2024, 15: 1537 (IF=16.6)
5. Herbgenomics: Decipher molecular genetics of medicinal plants,Innovation, 2022, 3(6): 100322. (IF=32.1)
6.Crocusgenome reveals the evolutionary origin of crocin biosynthesis.Acta Pharmaceutica Sinica B, 2023 (IF=14.5)
7.Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis,Horticulture Research, 2023, uhad150 (IF=8.7)Cover story
8. Genome analysis of the ancient tracheophyteSelaginella tamariscinareveals evolutionary features relevant to the acquisition of desiccation tolerance.Molecular Plant, 2018, 11: 983-994. (IF=27.5)SPOTLIGHT,ESI Highly Cited Paper
9. Advances in pharmacology, biosynthesis, and metabolic engineering ofScutellaria-specialized metabolites,Critical Reviews in Biotechnology, 2024, 44(2):302-318 (IF=9.0)
10. Novel processing strategies to enhance the bioaccessibility and bioavailability of functional components in wheat bran.Critical Reviews in Food Science and Nutrition, 2022, 10.1080/10408398.2022.2129582 (IF=10.2)
11. Comparative genomics reveal the convergent evolution of CYP82D and CYP706X members related to flavone biosynthesis in Lamiaceae and Asteraceae.Plant Journal, 2022, 109(5):1305-1318 (IF=7.2)
12. The genome ofCorydalisreveals the evolution of benzylisoquinoline alkaloid biosynthesis in Ranunculales.Plant Journal, 2022, 111(1):217-230 (IF=7.2)
13. Trends in Herbgenomics.SCIENCE CHINA Life Sciences, 2019, 62(3): 288-308. (IF=9.1)
14. The honeysuckle genome provides insight into the molecular mechanism of carotenoid metabolism underlying dynamic flower coloration.New Phytologist, 2020,227(3):930-943.(IF=9.4)
15. Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues ofSalvia miltiorrhizaand tanshinone biosynthesis.Plant Journal, 2015, 82:951-961. (IF=7.2)ESI Highly Cited Paper;TOP5 most cited articles over 2016-2017 (Plant Journal)
16. Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants.BMC Biology, 2020, 18: 63. (IF=5.4)HIGHLIGHT
17. Comparative Genome Analysis ofScutellaria baicalensisandScutellaria barbataReveals the Evolution of Active Flavonoid Biosynthesis.Genomics Proteomics and Bioinformatics, 2020, 18: 230-240. (IF= 9.5)
18. The 2-oxoglutarate-dependent dioxygenase superfamily participates in tanshinone production ofSalvia miltiorrhiza.Journal of Experimental Botany, 2017, 68 (9): 2299-2308. (IF= 6.9)
19. Precise species detection of traditional Chinese patent medicine by shotgun metagenomic sequencing.Phytomedicine,2018, 47: 40-47. (IF=7.9)
20. Genome-wide identification and functional characterization of 2,3-oxidosqualene cyclase genes inPhellodendron amurense.Industrial Crops and Products, 2024, 208, 117721. (IF=5.9)
出版著作
1.《藥用植物分子遺傳學》科學出版社2022
2.《本草基因組學-中藥組學的發展與未來》科學出版社2016
3.《本草基因組學》全國高等醫藥院校規劃教材科學出版社2018
4.《藥用植物品質生物學》科學出版社2019
5. “The Genome ofSalvia miltiorrhiza” of《TheSalvia miltiorrhizaGenome》Springer 2019
獎勵
1.中草藥國際通用DNA條形碼鑒定體系，世界中醫藥學會聯合會，中醫藥國際貢獻獎科技進步獎，一等獎，2018
2.黑龍江省高等教育和職業教育教學成果獎一等獎
3.瀕危重樓屬植物資源種質創新與産業化應用，中國産學研合作創新與促進獎，産學研合作創新成果獎二等獎，2024
授權專利
1.一種基于宏基因組的中成藥質量控制方法，2022，美國專利
2.參與西紅花苷合成的糖基轉移酶GjUGT94E13和GjUGT74F8的篩選鑒定及應用，2022
3.一種參與揮發性成分形成的類胡蘿蔔素裂解雙加氧酶編碼基因的篩選鑒定及應用，2022
4.一種參與金銀花花色變化的類蘿蔔素裂解雙加氧酶編碼基因的篩選鑒定及應用，2022
5.七葉樹2,3-氧化鲨烯環化酶及其編碼基因與應用，2023
6.催化β-香樹脂醇21位羟基化的CYP450酶蛋白及編碼基因與應用，2023
