孫善文 教授/博士生導師

聯系方式:

E-mail: sunshanwen@nefu.edu.cn

地址：黑龍江省哈爾濱市香坊區和興路26号

伟德官网下app官方网站（新逸夫教學樓）226房間

教育經曆：

2014-10至2019-04，德國拜羅伊特大學，博士，導師：Bettina Engelbrecht

2010-09至2014-07，中國科學院西雙版納熱帶植物園，碩士，導師：曹坤芳研究員

2006-09至2010-07，東北師範大學，城市與環境科學學院，學士

工作經曆：

2019-09至2021-04，電子科技大學，博士後，導師：鄒權教授

研究領域：

生物信息學，生物序列分析，植物功能基因挖掘，人工智能

科研項目：

主持國家自然基金委項目2項，伟德官网下app官方网站引進人才項目1項，中央高校項目1項，黑龍江省項目3項，各類項目到賬經費總額200餘萬元。

學術兼職：

JDSIS期刊編輯，Frontiers集團雜志的Guest Editor，主持專刊一份，Nature chemical biology等期刊審稿人

中國自動化學會委員

中國人工智能學會委員

中國計算機學會委員

發明專利：

一種RNA測序數據的基因表達量計算方法。專利号：ZL 2020 1 0603775.3

論文發表：

Xueying Xie, Lin Gui, Baixue Qiao, Guohua Wang, Shan Huang, Yuming Zhao, Shanwen Sun* (2024) Deep learning in template-free de novo biosynthetic pathway design of natural products. Briefings in Bioinformatics. 25(6): bbae495 (自動化學會生物信息學A類期刊，TOP期刊)

Baixue Qiao, Shuda Wang, Mingjun Hou, Haodi Chen, Zhengwenyang Zhou, Xueying Xie, Shaozi Pang, Chunxue Yang, Fenglong Yang, Quan Zou, Shanwen Sun* (2024) Identifying nucleotide-binding leucine-rich repeat receptor and pathogen effector pairing using transfer-learning and bilinear attention network. Bioinformatics. 40(10): btae581 (自動化學會生物信息學A類期刊)

Zhao Y, Gui L, Hou C, Zhang D, and Sun S* (2024) GwasWA: A GWAS one-stop analysis platform from WGS data to variant effect assessment. Computers in Biology and Medicine. 169:107820. (影響因子7.7，小類中科院一區，Top期刊)

Sun S, Ye X*, and Zou Q* (2023) Editorial: Machine learning on understanding the epigenetic mechanisms underlying plant adaptation and domestication. Front. Plant Sci. 14:1236787. (影響因子：5.6，中科院二區，Top期刊)

Chen B, Guo Y, Zhang X, Wang L, Cao L, Zhang T, Zhang Z, Zhou W, Xie L, Wang J, Sun S* (共同通訊), Yang C*, and Zhang Q* (2022) Climate-responsive DNA methylation is involved in the biosynthesis of lignin in birch. Front. Plant Sci. 13:1090967. (影響因子：5.6，中科院二區，Top期刊)

Wang X, Sun S (共同第一作者), Sedio B, Glomglieng S, Cao M, Cao K, Yang J, Zhang J*, and Yang J* (2022). Niche differentiation along multiple functional-trait dimensions contributes to high local diversity of Euphorbiaceae in a tropical tree assemblage. Journal of Ecology, 110, 2731–2744. (影響因子：6.381，中科院一區，Top期刊)

Ding K, Sun S (共同第一作者), Luo Y, Long C, Zhai J, Zhai Y, and Wang G* (2023) PlantCADB: A Comprehensive Plant Chromatin Accessibility Database. Genomics, Proteomics & Bioinformatics, 21, 311-323. (影響因子：11.5，中科院一區，Top期刊)

Sun S, Dong B*, and Zou Q*. Revisiting genome-wide association studies from statistical modelling to machine learning. Briefings in Bioinformatics. 22 (4), bbaa263. (影響因子：13.994，中科院一區，Top期刊)

Sun S, Xu L*, Zou Q*, and Wang G*. BP4RNAseq: a babysitter package for retrospective and newly generated RNA-seq data analyses using both alignment-based and alignment-free quantification method. Bioinformatics. 37 (9), 1319–1321. (影響因子：5.610，中科院一區，Top期刊)

Sun S*, Jung E, Gaviria J, and Engelbrecht B M J. Drought survival is positively associated with high turgor loss point in temperate perennial grassland species. Functional Ecology, 2020, 34:788-798. (影響因子：4.43，中科院一區，Top期刊)

Sun S, Ding H, Wang D*, and Han S*. Identifying antifreeze proteins based on key evolutionary information. Frontiers in Bioengineering and Biotechnology, 2020, 8:1-8. (影響因子：3.644，中科院二區)

Sun S, Wang C, Ding H, and Zou Q*. Machine learning and its applications in plant molecular studies. Briefings in functional genomics, 2020, 19:40-48. (影響因子：2.941，中科院二區)

Sun S, Ao C, Wang D*, and Dong B*. The frequencies of oppositely charged, uncharged polar, and β-branched amino acids determine proteins' thermostability. IEEE Access, 2020, 8:66839-66845. (影響因子：3.745，中科院二區，Top期刊)

Jung E, Gaviria J, Sun S, and Engelbrecht B M J*. Comparative drought resistance of temperate grassland species: testing performance trade-offs and the relation to distribution. Oecologia, 2020:1-14. (影響因子：2.915，中科院二區)

Bartlett M K*, Zhang Y, Yang J, Kreidler N, Sun S, et al. Drought tolerance as a driver of tropical forest assembly: resolving spatial signatures for multiple processes. Ecology, 2016, 97:503-514. (影響因子：4.7，中科院一區，Top期刊)

Bartlett M K*, Zhang Y, Kreidler N, Sun S, et al. Global analysis of plasticity in turgor loss point, a key drought tolerance trait. Ecology Letters, 2014, 17:1580-1590. (影響因子：8.665，中科院一區，Top期刊)

Bartlett M K*, Scoffoni C, Ardy R, Zhang Y, Sun S, et al. Rapid determination of comparative drought tolerance traits: using an osmometer to predict turgor loss point. Methods in Ecology and Evolution, 2012, 3:880-888. (影響因子：6.51，中科院一區，Top期刊)

本科人才培養：

論文：

1. Xueying Xie, Lin Gui, Baixue Qiao, Guohua Wang, Shan Huang, Yuming Zhao, Shanwen Sun* (2024) Deep learning in template-free de novo biosynthetic pathway design of natural products. Briefings in Bioinformatics. 25(6): bbae495 (本科生第一作者論文)

2. Baixue Qiao, Shuda Wang, Mingjun Hou, Haodi Chen, Zhengwenyang Zhou, Xueying Xie, Shaozi Pang, Chunxue Yang, Fenglong Yang, Quan Zou, Shanwen Sun* (2024) Identifying nucleotide-binding leucine-rich repeat receptor and pathogen effector pairing using transfer-learning and bilinear attention network. Bioinformatics. 40(10): btae581 (本科生參與論文)

專利：

1. 一種基于元分析構建基因調控網絡的方法 (本科生第一發明人)

2. 基于遷移學習的植物 NLR-無毒蛋白 Avr 對應關系識别方法 (本科生合作發明)

3. 一種植物抗鹽堿基因的識别方法及系統 (本科生第一發明人)

4. 一種基于深度學習的植物抗旱基因的識别方法 (本科生第一發明人)

課程：

生物信息學、生物實驗設計與統計分析